The study found that a deficiency in the molecule nicotinamide adenine dinucleotide, known as NAD, prevents a baby's organs from developing correctly in the womb.
It's been hailed a breakthrough.
"Arguably, it's the most important discovery for pregnant women since folate", Dunwoodie told Sophie Scott at ABC News, in reference to the landmark research that showed folic acid could reduce the incidence of spina bifida and other neural tube defects.
A genomic analysis revealed that both parents carried a mutation in a gene involved in the production of NAD - a vital molecule that contributes to energy production, DNA fix, and cell communication. However, the researchers then realized that the food they were feeding the mice was rich in vitamin B3, and helping the mice to create NAD by an alternative pathway.
For pregnant women, they added that current vitamin supplements that might not contain sufficient levels of vitamin B3.
A common dietary vitamin could save thousands of lives and prevent a range of birth defects after a world-first medical breakthrough by Australian researchers.
Basically, the researchers analysed the DNA of four families where the mothers had suffered multiple miscarriages or their babies were born with multiple birth defects.
New Orleans power turbine down; Pumping station capacity diminished
Constant duty pumps are smaller pumps that move water through the drainage system but don't actually move water out of the city. The pumps vary in size and capacity; some are as big as a garage and more than a century old.
Waddell, who was not involved in the study, warned that additional research in humans is needed before advising pregnant women to take B3 above and beyond the current United States recommendation of 18 milligrams a day.
"We need to identify those women at risk and identify a safe level of niacin for them to take to prevent miscarriages and birth defects". "And the prevention is so simple, it's a vitamin". "It bypasses the genetic problem", she said.
Researcher Professor Sally Dunwoodie said the study had identified a major cause of miscarriages as well as heart, spinal, kidney and cleft-palate problems in newborn babies.
"What's exciting for me is that we may be able to help people who have children who have developmental defects or who have had miscarriages", he said.
"But, we're not all the same in how we absorb nutrients", she said, adding that body mass index and diabetes can influence how a woman produces NAD.
Apparently, during their research, by increasing a pregnant woman's vitamin-B intake upped the embryo's NAD levels, which, in turn, could be indicitave of the potential to dramatically slash miscarriage and congenital malformations across the world.