After putting seven goals past Celtic two weeks ago in Group B, PSG and its impressive offensive armada of Neymar, Kylian Mbappe and Edinson Cavani will also try to improve what is already a tournament record of 24 goals in this season's group stage.
Read on for a full schedule and viewing details as well as a full explanation of the permutations for each group.
Tonight's fixtures (7.45pm): Barcelona vs.
Due to their superior head-to-head record against Real Madrid, Tottenham will qualify as winners of Group H.
CSKA Moscow must better Benfica's result to go through.
The changing focus towards substance over style under Ernesto Valverde is a change in ploy from recent years, but consistent results have given Barca a great chance of putting last season's woes behind them with major silverware this term. If both teams draw or lose, they will also qualify, courtesy of a better head-to-head record.
South Africa records thirty-six deaths in food related disease outbreak
Health Minister Aaron Motsoaledi has confirmed a countrywide outbreak of foodborne Listeria. This triggered a review of all cases diagnosed in both public and private hospitals.
None of the three Italian clubs in the competition have advanced yet, setting up a nail-biting finish to the group phase that is drawing comparisons with Italy's World Cup playoff loss to Sweden. Defensively they were bad first time round against Mourinho's men and, having scored seven in their last two games, United look good to win this by more than a goal. A point will confirm European football in the new year for the Scottish side, whilst Anderlecht can leapfrog them into third on goal difference providing they win 3-0. PSG are now in first place so Bayern must win by a four-goal margin to go through top.
Group winners winners will be drawn against sides who finished second (not from the same country or group as them).
Roma are going to beat Qarabag so all Atletico really have is Diego Simeone's hunger for revenge.
Antonio Conte's Blues still have plenty to play for too, as they need a win to guarantee top spot ahead of Roma.
Juventus will qualify in second with victory at Olympiacos or if Sporting fail to win. If you back the draw alongside Napoli (who know a win against Feyenoord could see them progress from Group F alongside City) and Manchester United both to win you have a treble paying in excess of 5/1 with bet365.
Olympiacos will finish bottom of Group D.