The fire wasn't enough to completely destroy the apartment, but the extent of the damage has forced the residents to move out.
"It was a huge wolf spider", Lyndsey Wisegarver, a caregiver for one of the tenants, told the publication.
It is unclear if the spider survived.
The fire chief said his crew was at least able to contain the fire to a bedroom closet and keep it from spreading into the attic or other units.
"It was a huge wolf spider", Wisegarver told the paper.
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As for Wisegarver and the two men living in the apartment, they are going to have to find another place to live. The residents managed to put the mattress fire out, but not before it had spread to a flag collection and drapes.
The residents unsuccessfully tried to quench the blaze using a garden hose but, before long, a fire was raging in the room.
Incredibly, it's not the first time someone has set fire to their home while attempting to kill a spider.
"The information regarding the "spider" was presented by civilian witnesses, at the scene of the fire, and is certainly part of our investigation", Gray said.
Fire officials say they responded to 2534 Waldon Street in Redding around noon for a fire at a townhouse.