Toward the north of that low's track, significant accumulating snow is also expected.
The counties placed under the winter storm warning in Minnesota include Brown, Nicollet, Le Sueur, Watonwan, Blue Earth, Waseca, Steele, Martin, Fairbault, Scott, Dakota, Rice and Goodhue counties.
A wintry mix with freezing rain is possible south of the heavy snow band.
A narrow swath from Nebraska to southeastern South Dakota, northwestern Iowa, southern Minnesota, north-central Wisconsin and the Upper Peninsula of MI will be buried under 6-12 inches of snow, with localized amounts up to 18 inches, AccuWeather said.
Areas of northeast Nebraska, including Albion, could receive 12 to 15 inches of snow.
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Sunday's high temperature is forecast to be 37 degrees in Columbus, so precipitation here will likely transition from rain to snow. Four-to-eight inches are predicted in the Denver foothills beginning Saturday night while up to seven inches are expected along the I-25 corridor into early Sunday, according to the NWS.
Strong winds continue as well, meaning that snow will be blowing around, diminishing visibilities and piling up in drifts.
A disturbance is moving through the region Saturday morning, bringing snow to parts of Nevada and Utah, including Salt Lake City. Overnight temperatures will drop into the 20's so the rain showers could turn into snow.
The Winter Weather Advisory and Storm Warnings remain in effect through Monday night.
Travelers should be prepared for "difficult driving conditions. across central or southern Minnesota, and western and northern Wisconsin", the forecasters' statement continued.