"Hopefully [he will play], I want him to come back soon and play because we enjoy watching him and hopefully he'll come back soon with Leicester and play at his level", Guardiola told a news conference.
'I love to play with the best sides and the best players because when you beat them you feel better, ' he said.
The two Manchester clubs are interested in signing the Englishman and is valued at £50million by the Foxes, who are reluctant to let him leave.
Form Manchester City, center-back John Stones is available again after the England global missed City's last two games due to illness and a minor knee injury.
City's opening goal, coming from Raheem Sterling in the third minute, set the tone and from there Pep Guardiola's men were simply unstoppable.
Just as the dust is settling on the Jose Mourinho vs Antonio Conte feud (for now) the Premier League has it's latest war of words.
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I asked him to repeat what he said and I think he realized what he said and tried to limit the damage. This is a serious accusation so he wants to defend it and that's all I really want to say on it.
But Guardiola insisted that City can not be blamed for their role in the saga, claiming the situation is no different to Leicester ing them last summer to negotiate a £25m deal for Kelechi Iheanacho.
The Belgian midfielder was about to be awarded the man of the match award by Sky Sports until Aguero crashed in his fourth goal of the day in stoppage time.
With a League Cup final date against Arsenal looming at the end of the month, Aguero says City are focused on silverware rather than individual plaudits.
With 12 to choose from, Aguero recalled the one he hit against Bayern Munich in the Champions League group stages in 2014.
With his equaliser midway through the first half, Jamie Vardy scored his fifth goal in all competitions against Manchester City while Pep Guardiola has been in charge. Leicester came to pick up Kelechi, we did it.
The 5-1 thumping means only Harry Kane has more Premier League goals than Argentina striker Aguero this campaign, while no one has produced more assists than De Bruyne.