The hosts are heading into the T20I rubber, hoping for change in fortunes as they were outplayed by the islanders in both the 50-over and Test formats.
Sri Lanka responded strongly with Mendis putting on 53 runs with fellow-opener Danushka Gunathilaka, who made 30, to put the Bangladesh bowlers on the back-foot.
Notably, Bangladesh were thrashed by 215 runs in Dhaka in the second Test after spinners Rangana Herath and Akila Dananjaya created problems on a track that spun from Day 1.
Sri Lanka have retained top order batsman Kusal Mendis for the upcoming two-match T20I series in Bangladesh after Kusal Perera, who was initially named in the 15-member squad, was ruled out of the series following medical advice on Tuesday (February 13). "There are also some concerns about Mushfiqur as he has niggles on his wrist".
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Sri Lanka, on the other hand, too have injury concerns and will be without Kusal Perera.
The Twenty20 series between Bangladesh and Sri Lanka gets underway on Thursday in Dhaka.
Bangladesh will be without the services of regular captain Shakib-al-Hasan and thus Mahmudullah will lead the side.
Kusal's 53 off 27 set the tone in Sri Lanka's pursuit of 194, before Shanaka (42 not) and Thisara (39no) finished the job in Mirpur to help the visitors to a 1-0 lead in the two-match series.