The post has now been viewed across the globe, racking up a million views on YouTube and well over a million on Facebook.
One person wrote: "The video of the down syndrome karaoke carpool on this morning had me in tears!"
World Down Syndrome Day is Wednesday, March 21, 2018 and its goal is to raise awareness around the world of what Down syndrome is and the vital role people with Down syndrome play in our society.
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"The decision is entirely left for women to decide what type of decent and respectful attire she chooses to wear". Saudi Arabia's interest in nuclear power is motivated by two concerns.
The idea for the video was put forward on a Facebook group called Designer Genes, set up for parents with children with Down syndrome. This group has parents of children with Down syndrome.
The families, who come from across the United Kingdom, recorded clips of themselves signing to the song, which became famous as part of the Twilight soundtrack.
Corden tweeted a second time, calling it "the most lovely Carpool Karoke ever". They then break out into the song.