It's understood two people were killed in the crash.
The plane is believed to have plummeted to the ground at around 12.20pm near Loanends Road and Nutts Corner.
Paramedics and three ambulance crews along with police officers and an air ambulance are at the scene.
The airport tweeted that it was running a normal service, and that the plane was not operating either to or from it.
No patients were taken from the scene of the crash about three miles from Belfast International Airport, the ambulance service said.
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The Air Accident Investigation Branch said it is sending a team to investigate the incident.
A SMALL AIRCRAFT has crashed near Belfast International Airport this afternoon.
Eyewitnesses saw the light plane crash in a field and explode.
Authorities said the airplane crashed near Belfast Airport Terminal.
An airfield in Enniskillen, Co Fermanagh, also said it was not involved in the flight. The BBC reported that there was a fire at the scene.
"This is an ongoing incident and no further information is available at this time".