Andres Iniesta returned to the scene of his greatest triumph in his penultimate game for Barcelona as the Spanish champion beat South Africa's Mamelodi Sundowns 3-1 in a friendly in Johannesburg on Wednesday.
The match, to be played at the FNB Stadium in Soweto, kicks off at 18:15.
Though Messi, Gerrard Pique and Philippe Coutinho all started from the bench, an otherwise strong Barca XI encountered few hiccups, aside from a Sibusiso Vilakazi consolation strike in the 76th minute.
Ousmane Dembele, Luis Suarez and Andre Gomes scored for Barcelona against the South African league victor in a game that formed part of South Africa's celebrations to mark 100 years since the birth of Nelson Mandela, the anti-apartheid icon who died in 2013. They surprised us a little bit because they were very fast.
Talking about the upcoming match, Masandawana head coach Pitso Mosimane said that he is looking forward to come up against one of the best football teams in world.
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"I'm proud of Masandawana, they played well they played the way I wanted them to play".
Without him, the Blaugrana lost away to Levante, a result which ended their unbeaten run in La Liga.
Ivorian Soumahoro was also at fault for the second goal, failing to cut off a Denis Suarez pass on 19 minutes and Luis Suarez made no mistake from close range.
Barca now return to Spain to prepare for their final game of the season at home to Real Sociedad on Sunday.