He was initially reported to have been diagnosed with an MCL sprain.
The competition is now wide open after Guice's season-ending injury. He had suffered a hyperextended knee (yes, the same knee) at LSU but opted against surgery, also per Rapoport.
Guice was injured in Washington's preseason opener at New England on Thursday night and could be seen on the sideline with ice on his knee.
Instead, Guice's National Football League career starts with a medical redshirt. Guice had appeared to be the front runner to start after an excellent performance in training camp. ACL tears typically take at least six months to recover from and the track record of being the same player has been mixed.
In Weeks 11-17, Perine averaged 2.65 yards after contact per attempt, ranking 12th among running backs with at least 100 attempts in said span. Both players are expected to make a full recovery and are looking forward to playing in 2019.
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beIN has one more season to run in its present contract with the new Premier League season getting underway on Friday evening.
Still, Guice's injury continues the streak of bad luck for the organization.
Washington has also had a recent history of their high-profile draft picks not being able to stay healthy.
Brady, 41, signed a two-year, $41m contract prior to last season.
Guice, a second-round rookie, suffered the injury during Week 1 of the preseason against the New England Patriots.
The team said tight end Manasseh Garner, a long shot to make the roster, is out for the season with an ACL injury.