Dozens have reportedly died after a major bridge had collapsed in the northern Italian city of Genoa.
The fire service said it was feared that cars that were on the motorway had plummeted when it suddenly gave way.
There have been reports of fatalities after a 650ft section of the Morandi Bridge fell in the north-western city, as well as claims that one person had been pulled alive from the rubble. Firefighters told The Associated Press that there are concerns about gas lines.
The collapse is shaping up to be a "huge tragedy", Infrastructure and Transport Minister Danilo Toninelli says.
The crossing, which was built on the A10 toll motorway in the 1960s, was last reconstructed in 2016.
An ambulance official said the service could only confirm two injured people so far, 'but we suppose there are unfortunately a lot of dead'.
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Italian authorities have said that a 200-metre section of the Morandi Bridge collapsed on Tuesday over an industrial zone.
Genoa is located between the sea and the mountains of northwestern Italy.
Video captured the sound of a man screaming: "Oh god, oh, god".
The fire department posted an image taken from below the collapsed span, showing a truck stopped just feet from where the bridge trails off into the open air.
National news agency ANSA said that authorities suspected that a structural weakness caused the collapse on Tuesday.