The fight promises to be Joshua's toughest bout since his thrilling stoppage of former champion Wladimir Klitschko at Wembley in April previous year.
"The one who's toughest will come out victorious". Joshua has promised a breaking down job, the crowd will want a knockout and Povetkin will be determined to crash the Wembley party.
The last time the 28-year-old fought at the national stadium, however, he defeated Wladimir Klitschko in stunning fashion, climbing off the canvas to stop the Ukrainian in the 11th round.
Joshua's last two world title bouts were at the Principality Stadium in Cardiff, where he beat Carlos Takam before adding the WBO belt in a points win over New Zealander Joseph Parker in March.
Wilder has 39 knockouts in 40 fights and has scored knockouts in each of his previous seven title defenses.
The fight has a reported £26m purse with Joshua expected to take home up to £20m while Povetkin will receive £6m.
Also after engaging in an icy final stare-down, Alexander Povetkin is feeling "no pressure" ahead of today's heavyweight clash with Anthony Joshua.
Povetkin, the 2004 Olympic super-heavyweight champion, lost to Klitschko in Moscow in 2013.
Hughes claims Liverpool ‘need’ to win the Premier League title
"It is a completely normal for an offensive player when you have times that you don't score". "I thought we were good", Henderson said .
Meanwhile, Joshua was over a stone-and-a-half heavier than Povetkin as they weighed in for their fight at Wembley on Friday, Skysports reports.
"It's very pleasant for me to see fans of mine here in England rooting for me".
"When I fought Klitschko, I was much weaker and in worse shape than I am now", he said.
"It's a very comfortable and good weight for me, I feel great", he said, via a translator.
Despite the weight advantage, Joshua insists he is agile enough to bring up his 22nd professional victory.
And having put Povetkin on the canvas, Price has now told Joshua of the Russian's weakness.
"Wembley is there - a date and a location - it's just the person who wants to step up and fight me".