Incidentally, the 94,000 FNB Stadium was where the Super Eagles won their last Nations Cup trophy in 2013, beating the resilient Stallions of Burkina Faso in the final.
The three-time African champions went into the lead in the ninth minute when Mkhwanazi deflected a cross from Kalu into his own net.
That would include Villarreal youngster Samuel Chukwueze, who made the match day squad against South Africa but he is still waiting to make his full worldwide debut.
"We had some problems in the first half, especially on the left side, but we played better in the second half and had some counter-attack opportunities".
"After reaching the World Cup, this was our second target, we did it", said Rohr after his players sealed qualification. The NFF [Nigeria Football Federation] couldn't make us come early.
Nigeria always looked risky with their forays and they were the most likely to find the breakthrough, which came nine minutes into the game when Bafana defender Buhle Mkhwanazi deflected Kalu Ojim's cross past keeper Itumeleng Khune.
"Our plan was to play it like a final". I hope to see him in a big team in Europe, in England or the championship.
"We know that we have only beaten them once and they have beaten us five times, it's going to be a tough encounter but we are very positive that we can beat them again tomorrow".
"I don't criticise the referee but maybe our captain was too fast technically for the linesman". "I think they will be with us in Cameroon", said Rohr.
Both teams tied 1-1 in a friendly in Nelspruit in March 2015 before the Bafana shocked the Eagles in Uyo 2-0 on Matchday 1 of the current qualifying series.
One such intricate build-up down the left flank saw the unsafe Saudi-based Ahmed Musa teed up on the edge of the area to force a diving save from Itumeleng Khune.
Scientists set to change definition of the kilogram
Le Grand K was compared with the various copies only once every 40 years, which made the calibration potentially inaccurate. Over 50 scientists have voted in a change which will see the 129-year-old method of defining a kilogram scrapped.