One of Europe's traditional financial powerhouses Manchester United meet the nouveau riche Paris Saint-Germain as the Champions League last 16 gets underway on Tuesday with both sides hoping to finally reap some reward on the biggest stage from record levels of investment.
This will certainly be a setback for Solskjaer but the Man United caretaker boss has yet another reason to be happy after Edinson Cavani picked up what looked to be a hamstring injury during PSG's 1-0 win over Bordeaux.
The Uruguay global was one of few PSG stars to start the match, as Tuchel kept the likes of Leandro Paredes and Kylian Mbappe in reserve ahead of the last-16 first leg at Old Trafford. He left the pitch moments later and was replaced by Kylian Mbappe at half-time.
"There is no good news for Edi this morning, there are still examinations today at our training centre, the club will speak a little later, but in my opinion, the news is not going to be very good", Tuchel said.
"I am anxious, but only because we are missing key players".
There was better news on Marco Verratti, though, with Tuchel confident the Italian midfielder will be fine to play against United despite only completing 60 minutes last time out.
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"There are lots of plan Bs now", Tuchel told reporters.
Cavani's fellow forward Neymar has already been ruled out of the United games with a broken metatarsal.
"If two or three key players are not there, it is our responsibility to find solutions". He will hopefully play 45 minutes, but we have to decide.
"If your key players are not there it's different".
"If he comes off, obviously I am anxious".
Bordeaux held PSG at home when the teams met in December, but they were undone late in the first half here as Nicolas de Preville fouled Thomas Meunier in the box, and Cavani netted from 12 yards.