The blackouts also have hit the oil industry.
Much of Venezuela has been without electricity for going on five days now due to a power outage that the government blames on what it calls "sabotage encouraged by the U.S".
Earlier, Pompeo blasted Russian Federation and Cuba for their continued support of Venezuelan President Nicolas Maduro, accusing them of keeping his regime afloat despite the will of the country's people.
U.S. Secretary of State Mike Pompeo announced Tuesday the withdrawal of all remaining American personnel from the U.S. embassy in Venezuela, citing the deteriorating political situation in the South American country.
Guaido said three of four electricity transformers servicing the area were knocked out.
"This decision reflects the deteriorating situation in Venezuela as well as the conclusion that the presence of USA diplomatic staff at the embassy has become a constraint on United States policy", Mr Pompeo wrote on Twitter.
Most US staff serving in Venezuela's capital Caracas had already been moved in January. More than 50 countries led by the USA have endorsed him.
"I am confident that they too understand the real threat to the Venezuelan people", Mr Pompeo said at a news conference on Monday.
Winston Cabas, the head of Venezuela's electrical engineers union, which opposes the government, disputed government allegations that the country's main hydroelectric dam was sabotaged last week.
In January, the United States pulled out all "non-emergency USA government employees" from the country and urged USA citizens not to travel to the South American nation.
But Mr Guaido said: "Nothing is normal in Venezuela, and we will not allow this tragedy to be considered normal, which is why we need this decree of a state of alarm".
Evrofinance said it is carrying out its activities normally despite the announcement and pledged to "meet its obligations to the clients and partners in full".
In January, President Nicolás Maduro of Venezuela won re-election, but Juan Guaidó, an opposition leader, declared himself the interim president, setting off a political crisis.
Mr Pompeo said that "India has been incredibly supportive of our efforts on Iran" where the USA has imposed strict sanctions after backing out of the multi-national agreement for Tehran to end its nuclear programme.
Nancy Pelosi Says It's 'Not Worth It' to Impeach President Trump
Rashida Tlaib, D-Mich., marched on Capitol Hill with impeachment supporters, and Rep. She added: " And he's just not worth it ". Other Democrats are more enthusiastic.