In the women's quarterfinals, Canada's 18-year-old Bianca Andreescu had an overwhelming 6-0, 6-1 victory over Spain's two-time Grand Slam victor Garbine Muguruza in 52 minutes to make her maiden Premier Mandatory semifinal. That's especially true after Novak Djokovic and No. 3 seed Alexander Zverev were upset in the other half of the bracket.
Nadal said his performance on a windy stadium court wasn't as good as his 6-3, 6-1 third-round win over Argentine Diego Schwartzman. "I think for me the plan worked".
Nadal was joined in the quarters by a less likely name as 19-year-old Serb Miomir Kecmanovic became the first lucky loser to reach the last eight at Indian Wells since the ATP's Masters 1000 series launched in 1990.
"I enjoy it", Federer said when asked of facing players for the first time.
Andreescu broke Muguruza at love and then served out the match after a deuce game, hitting consecutive forehand winners.
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World number four Roger Federer needed under an hour to defeat fellow Swiss Stan Wawrinka 6-3 6-4 and will next face Briton Kyle Edmund, who defeated Radu Albot in straight sets earlier in the day.
Struff is vying to reach a first Masters series quarter-final. That match features Austrian tennis star Dominic Thiem and Canadian great Milos Raonic. "He's got everything in the game".
Krajinovic hadn't dropped a set in winning his first three main-draw matches after two wins in qualifying but he was outclassed by Nadal in their one hour and 26 minute encounter. "Maybe because of the conditions".
The Spaniard will play Karen Khachanov next following the Russian's 6-4 7-6 (7-1) win over John Isner.
In the evening, Gael Monfils stretched his best start to a season to 15-3 after dominating Philipp Kohlschreiber 6-0, 6-2.
After a day of upsets which saw both world number ones, Novak Djokovic and Naomi Osaka, exit the singles, things went largely to plan at the Indian Wells Masters in California today.